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IMTEC-ScI70-Antibodies Rheumatism Autoimmune Diagnostics IMTEC

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IMTEC-ScI70-Antibodies.pdf (91.98 KB)
  • IMTEC-Scl70-Antibodies is an indirect solid-phase enzyme immunoassay (ELISA) for the qualitative and/or quantitative measurement of IgG class autoantibodies against Scl70 in human serum. The assay is intended for in vitro diagnostic use only as an aid in the diagnosis of scleroderma.

  • Autoantibodies to Scl70 are almost exclusively found in patients with systemic scleroderma with a frequency of 70%. Therefore these antibodies are considered to be marker antibodies of systemic scleroderma. Scl70 positive scleroderma patients have a more severe clinical course (involvement of internal organs) and poorer prognosis as centromere positive scleroderma patients.

  • Code ITC70028  96Tests

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