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IMTEC-Anti-C1q-Antibodies Rheumatism Autoimmune Diagnostics IMTEC

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IMTEC-Anti-C1q-Antibodies.pdf (85.29 KB)
  • IMTEC-Anti-C1q-Antibodies is an enzyme immunoassay (ELISA) for the quantitative measurement of IgG class autoantibodies against C1q in human serum. The assay is intended for in vitro diagnostic use only as an aid in the diagnosis of systemic lupus erythematosus and lupus nephritis.

  • Anti-C1q autoantibodies of the IgG type have been found in 17-46% of all patients with a systemic lupus erythematosus (SLE) and particularly in a large number of patients with lupus nephritis. It was also shown that an increased concentration of C1q autoantibodies has a sensitivity of 71%, a specificity of 92%, a positive predictive value of 50% and a negative predictive value of 97% for the development of renal involvement. Therefore, in patients with systemic LE, the detection of anti-C1q autoantibodies as well as detection of dsDNA autoantibodies are important criteria for determining potential renal involvement.

  • Code ITC59033  96Tests

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